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IDEXX Leukosis Blocking Ab Test

Enzootic Bovine Leukosis (EBL)/Bovine Leukemia Virus (BLV)

The IDEXX Leukosis Blocking Ab Test detects specific antibodies directed to the BLV gp51 antigen in both individual sera and pools of 10 sera. It is based on the competition between the BLV antibodies of the bovine serum and a peroxidase conjugate monoclonal anti-gp51 BLV antibody. It is an important complement to the indirect BLV ELISA that uses an ultrapurified BLV lysate. It is standardized to detect the European standard for serum (E5) diluted to 1:100 in negative bovine serum, according to the requirements of the Council Directive 64/432/EEC (modified on the December 11, 1984, June 26, 1991 and March 2001).

* Availability / Distribution: Outside the U.S.

Test details

Features

Blocking format
Monophasic kit

Part numbers and sizes

P02140-10 (10 plates/strips)

About Enzootic Bovine Leukosis (EBL)/Bovine Leukemia Virus (BLV)

Bovine leukemia virus (BLV) is a retrovirus that may cause lymphosarcoma in cattle. The virus resides in blood lymphocytes where circulating antibodies are unable to neutralize it. Therefore, once an animal is infected with BLV, it is infected for life.

BLV is economically significant to the producer because of premature culling or death as a result of lymphosarcoma. Another concern is the condemnation of carcasses at slaughter, which has a significant economic impact on the dairy and cattle industries. Losses from export restrictions are another economic concern of BLV infection. Countries that have bovine leukosis control programs require BLV-free certification prior to shipping cattle to their regions. Moreover, exporters of semen are under increasing pressure to ensure that their product is from a BLV-free animal in a BLV-free herd.