IDEXX SARS-CoV-2 RealPCR Test: Positive cases

Q: Has IDEXX detected a positive in any patients with the IDEXX SARS-CoV-2 RealPCR Test?

A: Yes, in a limited number of cases as described below. Each of these positives has been confirmed by independent testing by the United States Department of Agriculture National Veterinary Services Laboratories (USDA-NVSL). Additional clinical details of these cases are below:

May 22, 2020—A positive SARS-CoV-2 RealPCR result was detected in an eight-year-old male, neutered cat in Illinois.

Clinical History

This cat came from a household in which the owner had tested positive for COVID-19 previously but had completely recovered by the time the cat developed clinical signs. The cat presented to the veterinarian with oral ulcerative lesions, lethargy and a high fever. 

Laboratory results

FeLV antigen and FIV antibody by ELISA tests were negative. A feline coronavirus antibody by IFA was positive at 1:400. A Feline Upper Respiratory RealPCR Panel was negative for all pathogens, including those likely to cause oral ulcerations such as feline calicivirus and feline bartonella. The IDEXX SARS-CoV-2 RealPCR Test was positive. The result was confirmed internally in triplicate on the IDEXX test and on three United States Centers for Disease Control (US CDC) assays. The isolate was then confirmed positive by PCR and by sequencing at the USDA-NVSL on June 8, 2020.

Visit idexx.com/covid19-pet-test to learn more about the IDEXX SARS-CoV-2 (COVID-19) RealPCR Test and COVID-19 in pets.


May 26, 2020—A positive SARS-CoV-2 RealPCR result was detected in a three-year-old female, spayed Bengal cat in Minnesota.

Clinical History

Both owners of the Bengal cat had been sick and tested positive for COVID-19 in the weeks prior. The owners had fully recovered by the time the cat developed clinical signs. The cat presented to the veterinarian with a two-day history of lethargy and difficulty breathing. On physical exam, this normally fractious cat was very lethargic, with a high fever and harsh lung sounds. The cat did not have a cough or any eye or nasal discharge. Given the history of COVID-19 infection in the household, and because the clinical signs did not fit with those typically seen in cats with more common respiratory pathogens, the veterinarian elected to test for SARS-CoV-2 infection.  

Laboratory results

A Feline Upper Respiratory RealPCR Panel was also performed and was positive only for Mycoplasma felis. The IDEXX SARS-CoV-2 RealPCR test was positive with a moderate viral load. The result was confirmed internally in triplicate on the IDEXX test and on three US-CDC assays. The results were then further confirmed by PCR and by sequencing at USDA-NVSL.

View the OIE report for this case here.


July 1, 2020—A positive SARS-CoV-2 RealPCR result was detected in a 2 year old male/neutered dog in Texas.

Clinical History

Both owners of the dog were currently sick with COVID-19. The dog had been admitted to the veterinary clinic for boarding. Out of concern for the veterinary staff and other patients, the veterinarian elected to test the dog for SARS-CoV-2 infection. The dog had no clinical signs at the time of testing.

Laboratory results

The IDEXX SARS-CoV-2 RealPCR test was positive with a low viral load. The result was confirmed internally in triplicate on the IDEXX test and on three US-CDC assays. The results were then further confirmed by PCR and by sequencing at USDA-NVSL on July 7, 2020.

Visit idexx.com/covid19-pet-test to learn more about the IDEXX SARS-CoV-2 (COVID-19) RealPCR Test and COVID-19 in pets.

 


July 23, 2020—A positive SARS-CoV-2 RealPCR result was detected in a 9 year old female/spayed Boxer in Louisiana.

Clinical History

Both owners of the dog were currently sick with COVID-19. The dog had been admitted to the veterinary clinic for boarding. Out of concern for the veterinary staff and other patients, the veterinarian elected to test the dog for SARS-CoV-2 infection. The dog had no clinical signs at the time of testing.

Laboratory results

The IDEXX SARS-CoV-2 RealPCR test was positive with a low viral load. The result was confirmed internally in triplicate using the IDEXX test and also using three US-CDC assays. The results were then further confirmed by PCR and by sequencing at USDA-NVSL on August 3, 2020.

Visit idexx.com/covid19-pet-test to learn more about the IDEXX SARS-CoV-2 (COVID-19) RealPCR Test and COVID-19 in pets.


August 14, 2020—A positive SARS-CoV-2 RealPCR result was detected in a 4 year old M/N feline in Maryland.

Clinical History

One of the owners of this cat had recently tested positive for SARS-CoV-2 following exposure at a family gathering. This cat presented with a dry cough but no fever. Other cats within the household appeared healthy.

Laboratory results

The IDEXX SARS-CoV-2 RealPCR test was positive with a high viral load. The result was confirmed internally in triplicate using the IDEXX test and also using three US-CDC assays. The results were then further confirmed by PCR and by sequencing at USDA-NVSL on August 20, 2020.

Visit idexx.com/covid19-pet-test to learn more about the IDEXX SARS-CoV-2 (COVID-19) RealPCR Test and COVID-19 in pets.


August 19, 2020—A positive SARS-CoV-2 RealPCR result was detected in a 13 year old M/N feline in California.

Clinical History

Both owners had recently recovered from COVID-19 when this cat developed mild respiratory signs. Due to the exposure history, the veterinarian elected to test for SARS-CoV-2 infection.

Laboratory results

The IDEXX SARS-CoV-2 RealPCR test was positive with a low viral load. The result was confirmed internally in triplicate using the IDEXX test and also using three US-CDC assays. The results were then further confirmed by PCR and by sequencing at USDA-NVSL on August 24, 2020.

Visit idexx.com/covid19-pet-test to learn more about the IDEXX SARS-CoV-2 (COVID-19) RealPCR Test and COVID-19 in pets.


August 21, 2020—A positive SARS-CoV-2 RealPCR result was detected in a 12 year old M/N feline in Louisiana.

Clinical History

The cat developed respiratory signs three days after his owner tested positive for SARS-CoV-2 infection. Clinical signs included increased respiratory effort, sneezing and lethargy without fever.

Laboratory results

The IDEXX SARS-CoV-2 RealPCR test was positive with a high viral load. The result was confirmed internally in triplicate using the IDEXX test and also using three US-CDC assays. The results were then further confirmed by PCR and by sequencing at USDA-NVSL on August 26, 2020.

Visit idexx.com/covid19-pet-test to learn more about the IDEXX SARS-CoV-2 (COVID-19) RealPCR Test and COVID-19 in pets.

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