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NSAID—Diagnostic
Application
Liver
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ALT (alanine aminotransferase): ALT is a sensitive indicator of active liver-cell injury.
AST (asparate aminotransferase): With a shorter half-life than ALT, AST can complement ALT in indicating "active" liver-cell injury.
ALKP (alkaline phosphatase): ALKP can help detect cholestasis.
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Kidney
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BUN (blood urea nitrogen): An increase in BUN can indicate a decrease in glomerular filtration rate.
CREA (creatinine): An increase in creatinine can indicate a decrease in glomerular filtration rate, and may be a more specific indicator of kidney damage.
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Why should you use the NSAID Monitoring Panel?
Manufacturers recommend that all
patients on NSAID therapy be tested:
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Prior to initiating NSAID therapy—for a
baseline, including a general health profile, complete blood count,
electrolytes and a urinalysis
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During the trial period—using the NSAID
Monitoring Panel
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Periodically throughout NSAID therapy—monitoring
regularly using the NSAID Monitoring Panel
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